Sunday, 13 May 2018
Fasting for 24 hours regenerates stem cells, study finds
A new study points to one reason fasting may be good for our bodies, with evidence that a 24-hour gap in eating can flick a metabolic switch for regeneration in our digestive system.
By studying the effects of fasting on mice, a team of researchers at MIT found that just one day of calorie restriction substantially improves the ability for stem cells in the intestine to regenerate.
In the fasting mice, however, cells began to break down fatty acids instead of glucose. This stimulated the stem cells to become more regenerative.
“This study provided evidence that fasting induces a metabolic switch in the intestinal stem cells, from utilising carbohydrates to burning fat,” says David Sabatini, an MIT professor of biology and senior author of the paper, published in Cell Stem Cell.