Thursday, 28 November 2019

Anti-cholesterol jab twice a year could herald the end of statins


Taking statins every day to control cholesterol could soon become a thing of the past and be replaced instead by twice-yearly jabs.

Spectacular results from trials of an injectable drug called inclisiran show that it can slash 'bad' LDL cholesterol levels by more than 50% after just two weeks, and that after the jab, levels stay stable for six months.

Experts hope that the breakthrough treatment will get NHS approval within 18 months, and they are working on a longer-lasting version that could be given just once a year. 

Ref: https://www.dailymail.co.uk/news/article-7719131/Anti-cholesterol-jab-twice-year-herald-end-statins-win-NHS-approval.html

Moderate coffee consumption daily reduces metabolic syndrome


Coffee comes with the potential of reducing the risk of developing a major cardiovascular issue which is known for affecting more than one billion people across the globe, says a recent study.

A report from the Institute for Scientific Information on Coffee (ISIC) highlights the potential role of coffee consumption in reducing the risk of developing MetS (metabolic syndrome), that increases the risk of cardiovascular problems, including coronary heart disease and stroke.

During the symposium, Assistant Professor Giuseppe Grosso reviewed his own scientific research on the association between coffee consumption and MetS in Polish and Italian cohorts and explored the potential mechanistic perspectives behind the inverse association.

His research suggests that polyphenols contained in coffee may be involved in the inverse association, specifically phenolic acids and flavonoids. He also reviewed research that suggests that moderate coffee consumption is associated with a reduction of CVD, cancer, all-cause mortality and type 2 diabetes.

Ref: https://sg.news.yahoo.com/drinking-1-4-cups-coffee-daily-reduces-metabolic-044142986.html

Nail clubbing, curved nails or deformed fingers means trouble - updated

People with curved nails (or nail clubbing) or deformed fingers or toes, may have lung disease, heart disorders or other problems if they are not born with them (nail clubbing).

Schamroth's window test

Normal people will have a diamond shape gap between 2 fingers or toes as in A. If there is no gap as in B, it means the finger nails are curved, or nail clubbing.

If you have clubbed fingers, it is best to see a doctor. While it may be easy to panic, clubbed fingers often run in families.



Ref: https://www.nhs.uk/Tools/Documents/nail_abnormalities_a_visual_guide.html

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